Abhishek Tiwari

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry. This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals. The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection. The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications. Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance. The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

Deep Learning for Diffusion Tensor Imaging Estimation: Unlocking Sparse Diffusion MRI Mental health and neurological disorders are on the rise globally, yet timely diagnosis remains a challenge due to high costs, long scan durations, and limited imaging accessibility. This book presents a breakthrough in neuroimaging by harnessing cutting-edge deep learning technologies-Transformers and Convolutional Neural Networks-to revolutionize how sparse diffusion MRI data is processed and analyzed. Dr. Abhishek Tiwari introduces SwinDTI, an innovative framework that dramatically improves the estimation of diffusion tensor imaging (DTI) parameters using minimal data, significantly reducing scan times while preserving clinical accuracy. This pioneering work empowers clinicians and researchers to extract meaningful insights from limited imaging resources, making it a powerful tool for early diagnosis of neurodegenerative diseases such as Alzheimer's and Frontotemporal Dementia. Drawing on extensive experimentation with benchmark datasets like HCP, ADNI, NIFD, and MICCAI Quad22, this book offers a roadmap for future-ready neuroimaging solutions. It bridges the gap between artificial intelligence and healthcare, providing scalable, explainable, and efficient tools for modern medical practice. Whether you're a researcher, clinician, or technologist, this book offers deep insights into the synergy between neuroscience and AI-unlocking new possibilities in brain connectivity mapping and precision diagnostics. ""A transformative step toward democratizing advanced neuroimaging using deep learning.""

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed. Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

A comprehensive and authoritative exploration of Tempol (4-Hydroxy-TEMPO), an exceptional chemical compound with diverse applications in both scientific research and medical practice. This book delves into Tempol's unique properties, mechanisms of action, and its potential role in combating oxidative stress-related disorders. Includes a chapter devoted to the safe handling, storage, and disposal of Tempol in compliance with pharmaceutical regulations. The authors pay particular attention to pharmaceutical regulations in the industry. This book offers an in-depth exploration of Tempol (4-Hydroxy-TEMPO), covering its chemical, pharmaceutical, and medical applications, making it a valuable resource for researchers, academicians, and industry professionals. The chapters bridge chemistry, pharmacology, and medical sciences, detailing Tempol’s role in various fields such as terpenoid synthesis, cancer therapy, diabetic nephropathy, and ocular neuroprotection. The dedicated chapter emphasizes Tempol's safe handling, storage, and disposal, with a focus on adhering to pharmaceutical regulations, ensuring its practical utility for pharmaceutical and industrial applications. Mechanistic insights into Tempol's interaction with phenolic antioxidants and its role in oxidative stress inhibition provide theoretical depth, while discussions on industrial and therapeutic applications highlight its practical relevance. The inclusion of nano-formulation techniques for Tempol showcases cutting-edge approaches to enhance its bioavailability and efficacy, catering to the latest trends in drug delivery systems.

Globalization, Urbanization, and Sustainability: What Can We Do? provides students with an introduction to the multifaceted nature of civilization and its impact on our environment. The text explores the intricate interplay between globalization, urbanization, and sustainability, and examines the environmental and health impacts of modern society, including climate change, resource consumption, and waste. The book's nine chapters focus on a distinct aspect of globalization, urbanization, and sustainability, including historical perspectives on urbanism and trade, economic fundamentals of global capitalism, world financial and trade institutions, demography, poverty and economic development, public health, and steps individuals can take to preserve our world and act as good stewards of the earth. Designed to foster a critical awareness of the costs associated with modern systems of production and inspire sustainable solutions, Globalization, Urbanization, and Sustainability is an exceptional resource for courses and programs in environmental studies, urban planning, international studies, economics, public health and sustainability.

This book named "Concepts of Social Pharmacy" is designed for first-year diploma students to provide the basic skills and knowledge on the subject. The book is simple, comprehensive, well-documented, and student-friendly. Tables, figures, and flowcharts have been incorporated to easily understand the subject. The topics are addressed as per the hours specified in the syllabus. We hope this book will meet the needs and requirements of D. Pharmacy students. The chapters have been critically reviewed before being sent to the press.

This unique volume covers specific aspects of the biological chemistry of terpenoids. It provides extensive information related to classification, general methods of extraction and isolation of terpenoids, synthesis and pharmacological activities of monoterpenoids, synthesis and medicinal uses of diterpenoids, biogenesis of terpenoids, synthesis and medicinal uses of sesqui terpenoids and sesterpenoids. Some terpenes are also classified as diterpene alkaloids. Most of the terpenoids with diverse molecular structures are biologically active and are used for the treatment of various diseases such as cancer, malaria, inflammation, tuberculosis and infection, and this is discussed. Features:Activities and biological relationships of terpenes An accurate assessment of where and what terpenes can lead to Discusses how microbes, in particular the actinomycetales, have well over 400 different gene clusters that produce terpenes Arranged by biological activities and usage Provides information on eukaryotic enzymes that have been shown to be a source of “ethnobotanical” terpenes

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