Bruce Stillman

Previous Cold Spring Harbor Symposia have addressed many different aspects of RNA biology such as Mechanisms of Transcription (1998), The Ribosome (2001), Epigenetics (2004) and Regulatory RNAs (2006). The 84th Cold Spring Harbor Symposium focused on RNA Control & Regulation and provided a current synthesis of the enormous progress in our understanding of RNA's influence on cells and organisms and how, when aberrant, its effects may contribute to the progression of disease. It is rare to find such a wide-ranging perspective on this topic in one volume and this collection of papers will be valuable to investigators in many fields. The topics covered at the meeting included: RNA-Based Structures; RNA Modifications; Nuclear Localization of RNA; Quality Control & Editing; RNA & Gene Regulation; Cotranscriptional Splicing; Intron/Exon Boundaries; Alternative Polyadenylation; Transposon Control; Small Noncoding RNAs; Long Noncoding RNAs; RNA & Development; Membrane-Less Organelles; Phase Separation; RNA-Based Diseases; and Novel RNA Functions. Numerous speakers participated in interviews during the course of the Symposium week and this volume includes transcripts of those discussions and the Dorcas Cummings lecture, for the general public, which was given by Dr. Jennifer Doudna.

Previous Cold Spring Harbor Symposia have addressed many different aspects of RNA biology such as Mechanisms of Transcription (1998), The Ribosome (2001), Epigenetics (2004) and Regulatory RNAs (2006). The 84th Cold Spring Harbor Symposium focused on RNA Control & Regulation and provided a current synthesis of the enormous progress in our understanding of RNA's influence on cells and organisms and how, when aberrant, its effects may contribute to the progression of disease. It is rare to find such a wide-ranging perspective on this topic in one volume and this collection of papers will be valuable to investigators in many fields. The topics covered at the meeting included: RNA-Based Structures; RNA Modifications; Nuclear Localization of RNA; Quality Control & Editing; RNA & Gene Regulation; Cotranscriptional Splicing; Intron/Exon Boundaries; Alternative Polyadenylation; Transposon Control; Small Noncoding RNAs; Long Noncoding RNAs; RNA & Development; Membrane-Less Organelles; Phase Separation; RNA-Based Diseases; and Novel RNA Functions. Numerous speakers participated in interviews during the course of the Symposium week and this volume includes transcripts of those discussions and the Dorcas Cummings lecture, for the general public, which was given by Dr. Jennifer Doudna.

The 2018 Symposium on Brains & Behavior: Order & Disorder in the Nervous System explores the tremendous recent progress in neuroscience and technologies and how these advances may be used to improve brain health and address psychiatric and neurological disorders. Topics include: - Cellular basis of neurodegeneration- Memory systems and aging- Neural circuit of anxiety- Addicted brain: circuits and treatment frontiers- Sleep and sleep disorders- Hormonal regulation and mood disorders- Restoring vision- Cortico-striatal circuits in perception and action- Deep brain stimulation for psychiatry- Computational psychiatry- Development of social cognition- Brain machine interface- New techniques for human brain manipulation

The 2018 Symposium on Brains & Behavior: Order & Disorder in the Nervous System explores the tremendous recent progress in neuroscience and technologies and how these advances may be used to improve brain health and address psychiatric and neurological disorders. Topics include: - Cellular basis of neurodegeneration- Memory systems and aging- Neural circuit of anxiety- Addicted brain: circuits and treatment frontiers- Sleep and sleep disorders- Hormonal regulation and mood disorders- Restoring vision- Cortico-striatal circuits in perception and action- Deep brain stimulation for psychiatry- Computational psychiatry- Development of social cognition- Brain machine interface- New techniques for human brain manipulation

The 80th Cold Spring Harbor Symposium was held to mark the 150th anniversary of Gregor Mendel's landmark 1865 presentation of his paper "Experiments on Plant Hybridization," which laid the groundwork for modern genetics. The Symposium Proceedings addresses 21st Century Genetics: Genes at Work, and provides a current synthesis of genetic mechanisms and genome/chromosome biology. This volume spans a broad range of topics that reflect our current understanding of genetic mechanisms in humans and other organisms. Themes include chromosome biology and nuclear structure, topologically associating domains, gene-enhancer interactions, chromatin and epigenetics, gene regulation and control, developmental regulation, RNA controlling elements, maintenance of genome stability, nuclear receptors, circadian clocks and aging, and genome editing. The Conversations included in this volume are based on interviews conducted during the Symposium and offer a broader anecdotal perspective on this fascinating subject by many of the world's leading investigators.

This volume is based on presentations by the world-renowned investigators who gathered at the 74th annual Cold Spring Harbor Symposium on Quantitative Biology to celebrate the 150th anniversary of the publication of Charles Darwin's On the Origin of Species. It reviews the latest advances in research into evolution, focusing on the molecular bases for evolutionary change. The topics covered include the appearance of the first genetic material, the origins of cellular life, evolution and development, selection and adaptation, and genome evolution. Human origins, cognition, and cultural evolution are also covered, along with social interactions.

This volume is based on presentations by the world-renowned investigators who gathered at the 74th annual Cold Spring Harbor Symposium on Quantitative Biology to celebrate the 150th anniversary of the publication of Charles Darwin's On the Origin of Species. It reviews the latest advances in research into evolution, focusing on the molecular bases for evolutionary change. The topics covered include the appearance of the first genetic material, the origins of cellular life, evolution and development, selection and adaptation, and genome evolution. Human origins, cognition, and cultural evolution are also covered, along with social interactions.