Deepak Bhargava

Ameloblastome sind seltene gutartige odontogene Neoplasien, die selten b sartig werden. Bei soliden oder multizystischen Ameloblastomen ist in den meisten F llen die radikale Operation die Therapie der Wahl. Odontogene Tumoren umfassen eine Reihe von Erkrankungen des gut- und b sartigen Gewebes, die durch Zahnfehlbildungen gebildet werden. Ein guter Arzt sollte ber solide Kenntnisse ber orale Pathologien verf gen, was f r das Verst ndnis des komplizierten biologischen Verhaltens einer bestimmten Gruppe von L sionen von grundlegender Bedeutung ist. Der Ansatz zum Verst ndnis oraler Krankheitsprozesse unterst tzt den Kliniker bei der Erkennung spezifischer Zust nde und bei der Entwicklung von Differentialdiagnose, rationaler Behandlung und Prognose. Obwohl mehrere Artikel zu diesem Thema ver ffentlicht wurden, ist wenig ber das biologische Verhalten dieses Tumors bekannt. Eine sorgf ltige klinische Untersuchung in Kombination mit einer gr ndlichen bildgebenden Untersuchung zur Beurteilung der allgemeinen Aspekte der L sionen und ihrer R nder sowie ihrer inneren Architektur und ihrer Beziehung zu angrenzenden anatomischen Strukturen kann bei der Behandlungsplanung hilfreich sein.

Gli ameloblastomi sono rare neoplasie odontogene benigne che raramente diventano maligne. Nella maggior parte dei casi, la chirurgia radicale il trattamento di scelta per gli ameloblastomi solidi o multicistici. I tumori odontogeni comprendono una serie di disturbi del tessuto benigno e maligno che sono formati da malformazioni dentali. Un buon clinico dovrebbe avere una solida conoscenza delle patologie orali, fondamentale per comprendere l'intricato comportamento biologico di un particolare gruppo di lesioni. L'approccio per la comprensione dei processi della malattia orale assiste il clinico nel riconoscimento di condizioni specifiche e nello sviluppo della diagnosi differenziale, del trattamento razionale e della prognosi. Sebbene siano stati pubblicati diversi articoli sull'argomento, si sa poco sul comportamento biologico di questo tumore. Un attento esame clinico combinato con un'indagine di imaging approfondita per valutare gli aspetti generali delle lesioni e dei suoi margini, nonch la sua architettura interna e la sua relazione con le strutture anatomiche adiacenti, pu aiutare nella pianificazione del trattamento.

Ameloblastomas s o neoplasias odontog nicas benignas incomuns que raramente se tornam malignas. Na maioria dos casos, a cirurgia radical o tratamento de escolha para ameloblastomas s lidos ou multic sticos. Os tumores odontog nicos compreendem uma s rie de doen as do tecido benigno e maligno que s o formadas por malforma es dent rias. Um bom cl nico deve ter um conhecimento s lido das patologias orais, o que fundamental para a compreens o do intrincado comportamento biol gico de um determinado grupo de les es. A abordagem para a compreens o dos processos da doen a bucal auxilia o cl nico no reconhecimento de condi es espec ficas e no desenvolvimento do diagn stico diferencial, tratamento racional e progn stico. Embora v rios artigos tenham sido publicados sobre o assunto, pouco se sabe a respeito do comportamento biol gico desse tumor. Um exame cl nico cuidadoso combinado com uma investiga o de imagem minuciosa para avaliar os aspectos gerais das les es e suas margens, bem como sua arquitetura interna e sua rela o com as estruturas anat micas adjacentes, podem auxiliar no planejamento do tratamento.

Ameloblastomas are uncommon benign odontogenic neoplasms that rarely become malignant. In most cases, radical surgery is the treatment of choice for solid or multicystic ameloblastomas. Odontogenic tumors comprise a range of disorders of benign and malignant tissue which are formed by dental malformations. A good clinician should have a firm knowledge of oral pathologies, which is fundamental for understanding the intricate biological behavior of a particular group of lesions. The approach for the understanding of oral disease processes assists the clinician in the recognitions of specific conditions, and in the development of differential diagnosis, rational treatment and prognosis. Although several articles have been published on the subject, little is known regarding the biological behavior of this tumor. A careful clinical examination combined with a thorough imaging investigation to evaluate the general aspects of the lesions and its margins, as well as its internal architecture and its relationship to adjacent anatomical structures, can assist in treatment planning.

The head and neck is a complex region with a variety of lesions affecting it. The varied architectural and histopathological features play an important role in forming a conclusive diagnosis. Among the diverse types of cells seen in lesions is a type of cell called spindle cells, which appear fusiform or elongated. As the name suggests, this book attempts to compile and discuss the various pathologic lesions showing spindle cells in its histopathology.

The book describes many important molecular tools that are currently been used or will be used in diagnostic pathology as well as their application. In the future, the pathologist will continue to play a central role in diagnosis and it is conceivable the armamentarium of diagnostic test will induce many of these advances. Thus these changes will likely improve the understanding of diseases that affect the head and neck and the ability of the pathologist to render a correct diagnosis.