Falguni Mehta

Stammzellen im menschlichen K rper haben die einzigartige F higkeit, sich selbst zu erneuern und spezialisierte Zellen hervorzubringen. Aufgrund ihrer charakteristischen biologischen Eigenschaften, zu denen eine unbegrenzte Selbsterneuerung und ein breites Differenzierungspotenzial geh ren, verhalten sie sich anders als andere K rperzellen . Heute hat die Forschung im Bereich der Stammzelltechnologie rasante Fortschritte gemacht, so dass ihre direkte Nutzung in der Medizin und Zahnmedizin Realit t geworden ist und uns einem Paradigmenwechsel bei den Behandlungsans tzen und -modalit ten n her bringt. Mit ihrer vielversprechenden Regenerationsf higkeit hat ihre Anwendung insbesondere in der Kieferorthop die neue Wege zur Behandlung komplexer F lle, verschiedener Defekte und zur Verk rzung der Behandlungszeit er ffnet.

Le cellule staminali del corpo umano hanno una capacit unica di rinnovarsi e di dare origine a cellule pi specializzate. Si comportano in modo diverso dalle altre cellule somatiche grazie alle loro caratteristiche biologiche, che comprendono l'auto-rinnovamento illimitato e un ampio potenziale di differenziazione. Oggi, la ricerca sulla tecnologia delle cellule staminali ha fatto rapidi progressi, rendendo possibile il loro utilizzo diretto in medicina e odontoiatria, avvicinandoci a un cambiamento di paradigma negli approcci e nelle modalit di trattamento. Grazie alla sua promettente capacit di rigenerazione, le sue applicazioni, soprattutto in ortodonzia, hanno creato nuove strade per il trattamento di casi complessi, di vari difetti e per la riduzione dei tempi di trattamento.

As c lulas estaminais do corpo humano t m uma capacidade nica de se renovarem e de darem origem a c lulas mais especializadas, comportando-se de forma diferente das outras c lulas som ticas devido s suas propriedades biol gicas carater sticas, que incluem uma auto-renova o ilimitada e um amplo potencial de diferencia o. Atualmente, a investiga o no dom nio da tecnologia das c lulas estaminais tem feito r pidos avan os, tornando a sua utiliza o direta na medicina e na medicina dent ria uma realidade, aproximando-nos de uma mudan a de paradigma nas abordagens e modalidades de tratamento. Com a sua promissora capacidade de regenera o, as suas aplica es, especialmente em ortodontia, criaram novas vias para o tratamento de casos complexos, de v rios defeitos e para a redu o do tempo de tratamento.

Les cellules souches du corps humain ont la capacit unique de se renouveler et de donner naissance des cellules plus sp cialis es. Elles se comportent diff remment des autres cellules somatiques en raison de leurs propri t s biologiques caract ristiques qui comprennent un auto-renouvellement illimit et un large potentiel de diff renciation. Aujourd'hui, la recherche sur la technologie des cellules souches a fait des progr s rapides, faisant de son utilisation directe en m decine et en dentisterie une r alit qui nous rapproche d'un changement de paradigme dans les approches et les modalit s de traitement. Gr ce leur capacit prometteuse de r g n ration, leurs applications, en particulier en orthodontie, ont ouvert de nouvelles voies pour le traitement de cas complexes, de divers d fauts et pour la r duction de la dur e du traitement.

Dr. William J. Clarke is a renowned orthodontist best known for inventing the Twin Block Technique in 1977, which revolutionized orthodontic treatment by providing a non-surgical method for correcting malocclusions. He also developed the TransForce Appliances in 2004, which are designed to correct arch form and align anterior teeth invisibly. Dr. Clarke has been recognized for his contributions to orthodontics with several awards, including the first award from the British Orthodontic Society for outstanding contribution to the specialty and the IFUNA award for personal outstanding international service to functionalism and orthodontics.

Dr. Ravindra Nanda is a professor and Head of the Department of Craniofacial Sciences and Chair of the Division of Orthodontics at the University of Connecticut School of Dental Medicine. He is part of the founding faculty of the School of Dental Medicine. He has been at the University of Connecticut since 1972 and holds an Alumni Chair in the Orthodontics Division. He is an innovator of various orthodontic appliances. His research and clinical interests include adolescent and adult orthodontics, the biology of tooth mobility, craniofacial orthopedics, biomechanics, and developing efficient mechanics to deliver orthodontic care. Currently, Nanda is the editor-in-chief of Progress in Orthodontics, the associate editor of the Journal of Clinical Orthodontics, and on the editorial board of nine national and international orthodontic journals. He has authored and edited eight textbooks and more than 200 publications and peer-reviewed journals.

Fixed functional appliances in orthodontics normally known as "non-compliance Class II correctors" are devices used to correct jaw discrepancies, particularly Class II malocclusions, where the lower jaw is retropositioned. Unlike removable appliances, these are attached to the teeth and remain in place throughout the treatment, typically for several months. Fixed functional appliances work by applying continuous forces to influence jaw growth and dental alignment, making them suitable for growing patients, often during adolescence. They can also be used alongside braces to achieve optimal results. However, post pubertal growth is essential, for effective treatment, especially in case of skeletal modifications along with dentoalveolar compensation.

Stem cells in the human body have a unique ability to renew themselves and give rise to more specialized cells. They behave differently than other somatic cells due to their characteristic biological properties which include unlimited self-renewal and a broad differentiation potential. Today, research in Stem Cell Technology has made rapid advances making its direct utilization in Medicine and Dentistry a reality bringing us closer to a paradigm shift in treatment approaches and modalities. With its promising ability in regeneration, its applications especially in orthodontics has created newer avenues in treating complex cases, various defects and in reducing treatment time.

The growth of the craniofacial region and orthodontic and dentofacial orthopedic procedures are thought to be correlated with the shape and function of the masticatory muscles. The orthodontist can identify the functional goals of the orthodontic treatment by having a understanding of the relationship between various malocclusions and mandibular dysfunction. This evaluation must take into account the frequency of dysfunction and the broad etiological causes that are to blame. This review discusses how orofacial muscles contribute to the formation of malocclusions and dentoskeletal alterations, which is important for the diagnosis and formulation of treatment plans in orthodontic practice.

O Dr. David Mckendree Sarver nasceu a 1 de agosto de 1951 em Auburn, Alabama. Sarver sempre se interessou tanto pela ci ncia como pela pr tica da Ortodontia. Depois de obter o seu Mestrado em Ortodontia na Universidade da Carolina do Norte em 1979, regressou UAB e leccionou na Faculdade de Medicina Dent ria durante 15 anos, mantendo uma pr tica de Ortodontia a tempo inteiro em Vestavia, juntamente com uma prol fica produ o acad mica. O livro de Sarver, Esthetic Orthodontics and Orthognathic Surgery (Ortodontia est tica e cirurgia ortogn tica), o resultado da investiga o que tem vindo a realizar desde 1985. Recentemente, publicou o livro sobre est tica dentofacial intitulado "Dentofacial esthetics: from macro to micro" (Est tica dentofacial: do macro ao micro) em 2020. "Atualmente, a ortodontia envolve mais do que apenas endireitar os dentes", afirma Sarver, licenciado em 1977 pela Faculdade de Medicina Dent ria da UAB, "Hoje em dia, o foco est em todo o rosto."

Il dottor David Mckendree Sarver nato il 1 agosto 1951 ad Auburn, in Alabama. Sarver si sempre interessato sia alla scienza che alla pratica dell'ortodonzia. Dopo aver conseguito la laurea in Ortodonzia presso l'Universit della Carolina del Nord nel 1979, tornato alla UAB e ha insegnato nella Scuola di Odontoiatria per 15 anni, pur mantenendo una pratica ortodontica a tempo pieno a Vestavia, oltre a una prolifica produzione accademica. Il libro di testo di Sarver, Esthetic Orthodontics and Orthognathic Surgery, il risultato delle ricerche da lui condotte a partire dal 1985. Recentemente ha pubblicato un libro sull'estetica dentofacciale intitolato "Dentofacial esthetics: from macro to micro" (Estetica dentofacciale: dal macro al micro) nel 2020. "Al giorno d'oggi, l'ortodonzia non si limita a raddrizzare i denti", afferma Sarver, laureato nel 1977 presso la Scuola di Odontoiatria dell'UAB, "Oggi l'attenzione rivolta all'intero viso".

Dr. David Mckendree Sarver wurde am 1. August 1951 in Auburn, Alabama, geboren. Sarver hat sich schon immer sowohl f r die Wissenschaft als auch f r die Praxis der Kieferorthop die interessiert. Nachdem er 1979 seinen Master-Abschluss in Kieferorthop die an der University of North Carolina erworben hatte, kehrte er an die UAB zur ck und unterrichtete 15 Jahre lang an der School of Dentistry, w hrend er gleichzeitig eine Vollzeitpraxis f r Kieferorthop die in Vestavia unterhielt und eine rege wissenschaftliche T tigkeit aus bte. Sarvers Lehrbuch "Esthetic Orthodontics and Orthognathic Surgery" ist das Ergebnis seiner seit 1985 betriebenen Forschung. 2020 ver ffentlichte er ein Buch ber dentofaziale sthetik mit dem Titel "Dentofacial esthetics: from macro to micro". "Heutzutage geht es in der Kieferorthop die um mehr als nur um das Richten von Z hnen", sagt Sarver, der 1977 seinen Abschluss an der School of Dentistry der UAB gemacht hat, "heute steht das gesamte Gesicht im Mittelpunkt."

Le Dr David Mckendree Sarver est n le 1er ao t 1951 Auburn, en Alabama. Il s'est toujours int ress la fois la science et la pratique de l'orthodontie. Apr s avoir obtenu son dipl me de ma trise en orthodontie l'universit de Caroline du Nord en 1979, il est retourn l'UAB et a enseign l' cole de m decine dentaire pendant 15 ans, tout en conservant un cabinet d'orthodontie plein temps Vestavia, et en produisant une production acad mique prolifique. Le manuel de Sarver, Esthetic Orthodontics and Orthognathic Surgery, est le r sultat des recherches qu'il a men es depuis 1985. Il a r cemment publi un livre sur l'esth tique dento-faciale intitul "Dentofacial esthetics: from macro to micro" en 2020. "De nos jours, l'orthodontie ne se limite pas au redressement des dents", d clare Sarver, dipl m en 1977 de l' cole de m decine dentaire de l'UAB, "Aujourd'hui, l'accent est mis sur l'ensemble du visage."