Gautam Sethi

Cancer Metabolism: From Molecules to Medicine delivers groundbreaking insights and the latest research into the pivotal role of cancer metabolism in oncology and therapeutic strategies. This book underscores cancer metabolism as a foundational element of cancer biology, predating even the identification of oncogenes and tumor suppressors. It reveals how, unlike normal cells, cancerous cells modify their metabolic pathways to support malignancy, providing new avenues for therapeutic intervention. This book is divided into 16 chapters, delving into the core topics of cancer cell metabolism, metabolic disorders, and autophagy's role in tumor cell metabolism. These subjects illustrate the cellular fitness enhancement via metabolic reprogramming, offering tumors a selective edge through enhanced biosynthesis, altered bioenergetics, and redox balance. This book provides a thorough exploration of how these reprogrammed metabolic processes not only support cancer cell survival and proliferation but also present viable targets for innovative cancer treatments. “Cancer Metabolism: From Molecules to Medicine” serves as an essential resource for scientists and researchers seeking an in-depth understanding of the molecular mechanisms at play in cancer metabolism and its implications for therapy. Additionally, clinicians will find value in the comprehensive coverage of how these metabolic insights translate into novel treatment strategies, bridging the gap between basic research and clinical application. The book's focus on metabolic pathways as therapeutic targets offers practitioners new tools for combating cancer, making it a must-read for both the scientific and medical communities aiming to advance their knowledge and therapeutic capabilities in the dynamic field of cancer metabolism.

Liver Cancer and Phytomedicine systematically explores the potential of phytomedicines across three fundamental aspects of cancer management: prevention, sensitization, and therapy. This comprehensive book provides an extensive overview of the potential of important phytomedicines in managing liver cancer, encompassing areas such as prevention, sensitization therapy, modulation of gut microbiota, immunotherapy, and the emergence of phytonanomedicine. It serves as an invaluable resource for researchers and students in life sciences, biotechnology, and pharmaceutical sciences, offering insights into plant-derived therapeutics for liver cancer. The book explores the impact of phytomedicines on various facets of liver cancer biology, ranging from the tumor microenvironment to drug resistance pathways. Additionally, it discusses various clinical challenges and proposes strategies for transitioning to phytonanomedicine, providing valuable insights for researchers and clinicians engaged in developing liver cancer therapeutics.