Geeta I B

L'oxyg ne est un l ment omnipr sent et une substance importante pour la vie sur terre, en particulier pour la vie humaine, et il peut tre la fois benecial et nocif pour la vie . Les concentrations lev es d'oxyg ne se r v lent toxiques et peuvent endommager les tissus. Lorsque les cellules utilisent l'oxyg ne pour g n rer de l' nergie sous forme d'ATP dans les mitochondries, des radicaux libres sont cr s . Laformation excessive de radicaux libres qui n'est pas contrecarr e par l' limination cr e un "stress d'oxydation" qui estassoci diverses maladies bucco-dentaires et syst miques destructrices . Lestraitements dentaires utilisant des composites, des amalgames, des verre-ionom res, des mat riaux pour le canal radiculaire lling ou l'irrigation, ou des agents de blanchiment peuvent perturber l'hom ostasie redox orale en affectant labarri re antioxydante et en augmentant les dommages oxydatifs aux prot ines salivaires, aux lipides et l'ADN . L'ajout d'antioxydants aux mat riaux dentaires ou l'application d'une th rapie antioxydante pendant le traitement dentaire pourrait prot ger le patient contre les effets n fastes du stress oxydatif dans la cavit buccale.

L'ossigeno un elemento ubiquitario e una sostanza importante per la vita sulla terra, soprattutto per quella umana, e pu essere sia benecial che dannoso per la vita. Concentrazioni elevate di ossigeno risultano tossiche e possono danneggiare i tessuti. Quando le cellule utilizzano l'ossigeno per generare energia sotto forma di ATP nei mitocondri, si creano radicali liberi . L'eccessiva formazione di radicali liberi, che non viene contrastata dalla loro rimozione, crea uno "stress da ossidazione" che associato a varie malattie distruttive del cavo orale e del sistema. Iltrattamento dentale con l'uso di compositi, amalgame, vetro-ionomeri, materiali per il canale radicolare lling o per l'irrigazione, o agenti sbiancanti pu disturbare l'omeostasi redox orale influenzando la barriera antiossidante e aumentando il danno ossidativo alle proteine salivari, ai lipidi e al DNA. Si suggerisce che l'aggiunta di antiossidanti ai materiali dentali o la terapia antiossidante applicata durante il trattamento odontoiatrico possa proteggere il paziente dagli effetti nocivi dello stress ossidativo nel cavo orale.

Oxygen is an ubiquitous element and an important substance for life on earth especially for human life and it can both be beneficial and harmful to life. High and soaring concentration of oxygen are found to be toxic, and can damage tissues. When cells use oxygen to generate energy in the form of ATP in the mitochondria, free radicals are created. Excessive free radicals formation that is not counteracted by the removal, creates 'oxidation stress' which is associated with various oral and systemic destructive diseases. Dental treatment with the use of composites, amalgams, glass-ionomers, materials for root canal flling or irrigation, or whitening agents can disturb oral redox homeostasis by affecting the antioxidant barrier and increasing oxidative damage to salivary proteins, lipids, and DNA. It is suggested that the addition of antioxidants to dental materials or antioxidant therapy applied during dental treatment could protect the patient against harmful effects of oxidative stress in the oral cavity.

Contrary to traditional medicine modalities such as disinfectants and antibiotics, Ozone is quite economical which will make a marked reduction in medical cost and invalidity. Dentistry is presently improving with the induction of modern science into practice. Ozone therapy has been more beneficial than present conventional therapeutic modalities which follow a minimally invasive and conservative application to dental treatment. The exposition of molecular mechanisms of ozone further benefits practical function in dentistry. Treating patients with ozone therapy lessens the treatment time with an immense deal of variation and it eradicates the bacterial count more specifically. The treatment is painless and increases the patients' tolerability and fulfillment with minimal adverse effects. Contraindication of this controversial method should never be forgotten.