Himanshu Bhutani

Le d veloppement d'additifs chirurgicaux bioactifs pour r guler l'inflammation et augmenter la vitesse du processus de gu rison est l'un des grands d fis de la recherche clinique. Dans ce sens, la fibrine riche en plaquettes (PRF) appara t comme une alternative naturelle et satisfaisante avec des r sultats favorables et de faibles risques. Ce qui suit est un r sum de la litt rature pertinente concernant la technique d'utilisation de la PRF, en se concentrant sur sa pr paration, ses avantages et ses inconv nients dans les applications cliniques. Le PRF, seul ou en combinaison avec d'autres biomat riaux, semble pr senter plusieurs avantages et indications tant en m decine qu'en dentisterie, car il s'agit d'une technique peu invasive pr sentant de faibles risques et des r sultats cliniques satisfaisants.

The development of bioactive surgical additives to regulate the inflammation and increase the speed of healing process is one of the great challenges in clinical research. In this sense, platelet rich fibrin (PRF) appears as a natural and satisfactory alternative with favourable results and low risks. The following is to summarize the relevant literature regarding the technique of using PRF, focusing on its preparation, advantages, and disadvantages of using it in clinical applications. PRF alone or in combination with other biomaterials seems to have several advantages and indications both for medicine and dentistry, due it is a minimally invasive technique with low risks and satisfactory clinical results.

Toxins are usually considered to be damaging agents; however, they may be very helpful in the therapy of human illness. Botulinum neurotoxin (BTX) was the first microbial protein to be administered by injection to be used therapeutically in humans. BTX has appeared as one of the most multipurpose therapeutic agents in modern medicine with more clinical apps than any other presently on the market. With a better understanding of the cellular mechanisms of botulinun neurotoxin and the advances in biotechnology, future botulinun neurotoxin products are likely to be even more effective and customized to the specific indications and tailored to the needs of patients. Its increasing implementation, under various circumstances, makes it the most versatile drug on the market, spanning almost all medical specialties. Although deemed efficient and secure, there are still many constraints, such as injection-related discomfort, comparatively brief length of reaction, the chance of immunogenicity, and high.