Ka-Meng Lei

This book describes the complete design of CMOS-based multi-nuclear NMR/MRI microsystems. The authors emphasize optimizing semiconductor chip design to enhance the performance of compact CMOS-based NMR/MRI systems. They also discuss the integrated circuit design of customized modules, such as 3-D gradient controllers specifically for MRI, high-resolution multi-phase generators for advanced composite radio-frequency excitation pulse synthesis, etc. The integration of these specific modules not only drives system innovation but also expands functionality. Discusses developments in CMOS integrated circuit design for miniaturized NMR/MRI platforms over recent decades;Focuses on key integrated circuit design considerations for transceivers in compact NMR systems;Details the design of application-specific integrated circuits (ASICs) for a miniaturized 3-D MRI platform and a compact multi-nuclei NMR/MRI system, both featuring a portable magnet, for enhanced accessibility.

The book Handheld Total Chemical and Biological Analysis Systems: Bridging NMR, Digital Microfluidics, and Semiconductors centers on the complete design of Nuclear Magnetic Resonance (NMR) microsystems for in vitro chemical and biological assays based on semiconductor chips and portable magnet. Different sensing mechanisms for CMOS in vitro assay are compared, key design criteria of the CMOS transceiver for NMR measurement are revealed, and system-level optimizations of the CMOS NMR platform utilizing digital microfluidic and diverse functions of the CMOS technology are discussed. Two CMOS NMR platforms are implemented, each of these focuses on different aspect of optimization.

The book Handheld Total Chemical and Biological Analysis Systems: Bridging NMR, Digital Microfluidics, and Semiconductors centers on the complete design of Nuclear Magnetic Resonance (NMR) microsystems for in vitro chemical and biological assays based on semiconductor chips and portable magnet. Different sensing mechanisms for CMOS in vitro assay are compared, key design criteria of the CMOS transceiver for NMR measurement are revealed, and system-level optimizations of the CMOS NMR platform utilizing digital microfluidic and diverse functions of the CMOS technology are discussed. Two CMOS NMR platforms are implemented, each of these focuses on different aspect of optimization.