Matthew Stephenson

“A Meteor of Intelligent Substance” “Something was Missing in our Culture, and Here It Is” Liberties – A Journal of Culture and Politics features new essays and poetry from some of the world's best writers and artists to inspire and impact the intellectual and creative lifeblood of our current culture and today's politics. This summer issue of Liberties includes: Elliot Ackerman on Veterans Are Not Victims; Durs Grünbein on Fascism and the Writer; R. B. Kitaj’s Three Tales; Thomas Chatterton Williams on The Blessings of Assimilation; Anita Shapira on The Fall of Israel’s House of Labor; Sally Satel on Woke Medicine; Matthew Stephenson On Corruption’s Honey and Poison; Helen Vender on Wallace Stevens; David Haziza on Illusions of Immunity; Paul Berman on the Library of America; Clara Collier’s nostalgia for strong women in film; Michael Kimmage on American Inquisitions; Leon Wieseltier (editor) on the high price of Stoicism; Celeste Marcus (managing editor) on a Native American Tragedy; and new poetry from Adam Zagajewski, A. E. Stallings, and Peg Boyers.

In recent decades, there has been enormous growth in biologics research and development, with the accompanying development of biological assays for emerging products. In parallel, there have been substantial advances in statistical methodology, as well as technological advances in computer power, enabling new techniques to be implemented via statistical software. Biostatistics for Bioassay presents an overview of the statistical analysis techniques that are needed in order to report the results of biological assays. These assays are needed for testing all biological medicines, such as vaccines and cell therapies, to allow them to be released for use. Beginning with consideration of the performance characteristics required of a bioassay, including accuracy, precision, and combinations of these two attributes, the book builds a framework for statistical bioassay design. Features: Explains the statistical methods needed at each stage of the lifecycle of a bioassay Describes the demonstration of the bioassay’s performance, known as validation Covers the statistical techniques for monitoring the bioassay’s performance over time Details how to transfer the bioassay to another laboratory or replace critical reagents Provides examples at every stage, to allow the reader to work through the techniques and consolidate their understanding The book provides a resource for interested bioassay analysts, and statisticians working with bioassays. In bringing together best practices in statistics across the bioassay lifecycle into a single volume, it aims to provide a comprehensive and useful textbook for statistical analysis in bioassay.

In recent decades, there has been enormous growth in biologics research and development, with the accompanying development of biological assays for emerging products. In parallel, there have been substantial advances in statistical methodology, as well as technological advances in computer power, enabling new techniques to be implemented via statistical software. Biostatistics for Bioassay presents an overview of the statistical analysis techniques that are needed in order to report the results of biological assays. These assays are needed for testing all biological medicines, such as vaccines and cell therapies, to allow them to be released for use. Beginning with consideration of the performance characteristics required of a bioassay, including accuracy, precision, and combinations of these two attributes, the book builds a framework for statistical bioassay design. Features:Explains the statistical methods needed at each stage of the lifecycle of a bioassayDescribes the demonstration of the bioassay’s performance, known as validationCovers the statistical techniques for monitoring the bioassay’s performance over timeDetails how to transfer the bioassay to another laboratory or replace critical reagentsProvides examples at every stage, to allow the reader to work through the techniques and consolidate their understandingThe book provides a resource for interested bioassay analysts, and statisticians working with bioassays. In bringing together best practices in statistics across the bioassay lifecycle into a single volume, it aims to provide a comprehensive and useful textbook for statistical analysis in bioassay.

Following the popular and accessible at a Glance format, Vascular and Endovascular Surgery at a Glance demystifies the important concepts of vascular disease and vascular surgery. Featuring in-depth details of common vascular topics, to rarer presentations, this is an ideal guide for those interested in a variety of subjects relating to this rapidly expanding area. This is a must-read for any specialist at all levels who has an on-going commitment to vascular disease management and medical education. Vascular and Endovascular Surgery at a Glance: • Comprehensively covers the key concepts and core practical procedures with superb illustrations • Is a brilliant companion to the emerging curriculum for specialist vascular training • Is an excellent source of information and management guidelines for interdisciplinary specialties • Includes a companion website at www.ataglanceseries.com/vascular featuring a wide range of interactive multiple choice questions This title forms a succinct overview of vascular disease management, giving salient points relevant to general surgery examinations, for those requiring an in-depth yet manageable introduction to vascular diseases, and for those entering this prevalent field as a stand-alone specialty.

Thinking about a surgical career? About to start surgical training? Do you know what to expect and how to thrive? The Hands-on Guide to Surgical Training is the ultimate, practical guide for medical students and junior doctors thinking about taking the plunge into surgery, and also for surgical trainees already in training. It’s full of invaluable, practical information and career guidance to ensure you get the most out of your surgical career. It offers general guidance and advice on surgical training, together with detailed information on each of the nine surgical subspecialties, each written by seniors and consultants, as you make both clinical and career-based choices. Undoubtedly one of the most comprehensive resources for surgical trainees available, The Hands-on Guide to Surgical Training will be essential reading throughout your training and surgical career. Take the stress out of surgical training with The Hands-on Guide!

A unique blend of integrated video and book content, How to Operate provides a comprehensive, multimedia training resource for medical students, junior doctors, MRCS candidates and surgeons in training. The three DVDs present over 40 of the most common general, urological, ENT and orthopaedic surgical procedures, complete with step-by-step commentary from experienced surgical consultants. At key points during each procedure, the frame freezes so that anatomical structures and pathology are ‘drawn’ onto the frame for clarity and to reinforce learning. The 10 hours of video is supported by an accompanying book containing an introduction to each procedure, a thorough explanation of the operation mirroring the video with relevant video stills, and bullet point summaries which can be used as OSCE-style checklists. With a foreword by John Black, President of the Royal College of Surgeons, How to Operate is a truly comprehensive learning resource for all budding surgeons. All you need to become a surgeon is here – scalpel not included!