Qi Liang

This brief provides a comprehensive review of the rapidly expanding field of cavitation and bubble dynamics, covering the discussion of bubble dynamics equations, bubble oscillation dynamics, theoretical prediction models of jets, and high-speed photography technology. Among them, the core formulas, important research methods, and typical results related to bubble oscillation and collapse dynamics are systematically and comprehensively introduced. Specifically, in terms of the bubble dynamics equations, several classical dynamic equations utilized to describe the radial motion of the spherical bubble, cylindrical bubble, and the bubble in a droplet are derived and compared. In terms of the bubble oscillation dynamics, based on the perturbation method, multi-scale method, and Laplace transform method, the nonlinear oscillation characteristics of the bubble in free oscillation and driven oscillation are analyzed. In terms of the jet prediction theory, the Kelvin impulse model and various boundary treatment methods are given in detail, and the jet direction, intensity, and spatial sensitivity caused by the bubble collapse near various boundaries are discussed. In terms of the bubble collapse visualization based on the high-speed photography, taking the laser-induced bubble as an example, the system composition, operation process and experimental layout of the high-speed photography experimental platform are introduced, and a large number of typical bubble collapse deformation, jet evolution and shock wave propagation characteristics obtained from experiments are demonstrated. This book is intended for academic researchers and graduate students in fluid dynamics, aiming to consolidate the basic theory, physical mechanism, and latest progress in the field of bubble dynamics.

This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the “post-structural biology” era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.