S. Nassir Ghaemi

The second edition of a clear and accessible guide to the application of statistics in psychiatric practice. The book expertly describes statistical concepts in clear and simple terms, with minimal mathematical content, making it the ideal resource for busy mental health professionals. Fully revised throughout, it features five new chapters covering key advances in the field and important topics in greater detail. Amongst the key concepts discussed in this edition are the logic of randomization, clinical trials, the overuse of p-values, understanding effect sizes, meta-analysis and why clinical experience is limited by observational confounding bias. Featuring a wealth of clinical examples, on topics of high importance or controversy in psychiatry, plus explanations and reasoning, to give clinicians a better understanding of how to apply research to their practice.

Clinical Psychopharmacology offers a comprehensive guide to clinical practice that explores two major aspects of the field: the clinical research that exists to guide clinical practice of psychopharmacology, and the application of that knowledge with attention to the individualized aspects of clinical practice. The text consists of 50 chapters, organized into 6 sections, focusing on disease-modifying effects, non-DSM diagnostic concepts, and essential facts about the most common drugs. This innovative book advocates a scientific and humanistic approach to practice and examines not only the benefits, but also the harms of drugs. Providing a solid foundation of knowledge and a great deal of practical information, this book is a valuable resource for practicing psychiatrists, psychiatric nurse practitioners, medical students and trainees in psychiatry, as well as pharmacists.

In a culture obsessed with youth, financial success, and achieving happiness, is it possible to live an authentic, meaningful life? Nassir Ghaemi, director of the Mood Disorder Program at Tufts Medical Center, reflects on our society's current quest for happiness and rejection of any emotion resembling sadness. On Depression asks readers to consider the benefits of despair and the foibles of an unexamined life. Too often depression as disease is mistreated or not treated at all. Ghaemi warns against the "pretenders" who confuse our understanding of depression-both those who deny disease and those who use psychiatric diagnosis "pragmatically" or unscientifically. But experiencing sadness, even depression, can also have benefits. Ghaemi asserts that we can create a "narrative of ourselves such that we know and accept who we are," leading to a deeper, lasting level of contentment and a more satisfying personal and public life. Depression is complex, and we need guides to help us understand it, guides who comprehend it existentially as part of normal human experience and clinically as sometimes needing the right kind of treatment, including medications. Ghaemi discusses these guides in detail, thinkers like Viktor Frankl, Rollo May, Karl Jaspers, and Leston Havens, among others. On Depression combines examples from philosophy and the history of medicine with psychiatric principles informed by the author's clinical experience with people who struggle with mental illness. He has seen great achievements arise from great suffering and feels that understanding depression can provide important insights into happiness.

This is the first book-length historical critique of psychiatry's mainstream ideology, the biopsychosocial (BPS) model. Developed in the twentieth century as an outgrowth of psychosomatic medicine, the biopsychosocial model is seen as an antidote to the constraints of the medical model of psychiatry. Nassir Ghaemi details the origins and evolution of the BPS model and explains how, where, and why it fails to live up to its promises. He analyzes the works of its founders, George Engel and Roy Grinker Sr., traces its rise in acceptance, and discusses its relation to the thought of William Osler and Karl Jaspers. In assessing the biopsychosocial model, Ghaemi provides a philosophically grounded evaluation of the concept of mental illness and the relation between evidence-based medicine and psychiatry. He argues that psychiatry's conceptual core is eclecticism, which in the face of too much freedom paradoxically leads many of its adherents to enact their own dogmas. Throughout, he makes the case for a new paradigm of medical humanism and method-based psychiatry that is consistent with modern science while incorporating humanistic aspects of the art of medicine. Ghaemi shows how the historical role of the BPS model as a reaction to biomedical reductionism is coming to an end and urges colleagues in the field to embrace other, less-eclectic perspectives.

This is the first book-length historical critique of psychiatry's mainstream ideology, the biopsychosocial (BPS) model. Developed in the twentieth century as an outgrowth of psychosomatic medicine, the biopsychosocial model is seen as an antidote to the constraints of the medical model of psychiatry. Nassir Ghaemi details the origins and evolution of the BPS model and explains how, where, and why it fails to live up to its promises. He analyzes the works of its founders, George Engel and Roy Grinker Sr., traces its rise in acceptance, and discusses its relation to the thought of William Osler and Karl Jaspers. In assessing the biopsychosocial model, Ghaemi provides a philosophically grounded evaluation of the concept of mental illness and the relation between evidence-based medicine and psychiatry. He argues that psychiatry's conceptual core is eclecticism, which in the face of too much freedom paradoxically leads many of its adherents to enact their own dogmas. Throughout, he makes the case for a new paradigm of medical humanism and method-based psychiatry that is consistent with modern science while incorporating humanistic aspects of the art of medicine. Ghaemi shows how the historical role of the BPS model as a reaction to biomedical reductionism is coming to an end and urges colleagues in the field to embrace other, less-eclectic perspectives.

Accessible and clinically relevant, A Clinician's Guide to Statistics and Epidemiology in Mental Health describes statistical concepts in plain English with minimal mathematical content, making it perfect for the busy health professional. Using clear language in favour of complex terminology, limitations of statistical techniques are emphasized, as well as the importance of interpretation - as opposed to 'number-crunching' - in analysis. Uniquely for a text of this kind, there is extensive coverage of causation and the conceptual, philosophical and political factors involved, with forthright discussion of the pharmaceutical industry's role in psychiatric research. By creating a greater understanding of the world of research, this book empowers health professionals to make their own judgments on which statistics to believe - and why.

Because most psychiatric illnesses are complex phenomena, no single method or approach is sufficient to explain them or the experiences of persons who suffer from them. In The Concepts of Psychiatry S. Nassir Ghaemi, M. D. argues that the discipline of psychiatry can therefore be understood best from a pluralistic perspective. Grounding his approach in the works of Paul McHugh, Phillip Slavney, Leston Havens, and others, Ghaemi incorporates a more explicitly philosophical discussion of the strengths of a pluralistic model and the weaknesses of other approaches, such as biological or psychoanalytic theories, the biopsychosocial model, or eclecticism. Ghaemi's methodology is twofold: on the one hand, he applies philosophical ideas, such as utilitarian versus duty-based ethical models, to psychiatric practice. On the other hand, he subjects clinical psychiatric phenomena, such as psychosis or the Kraepelin nosology, to a conceptual analysis that is philosophically informed. This book will be of interest to professionals and students in psychiatry, as well as psychologists, social workers, philosophers, and general readers who are interested in understanding the field of psychiatry and its practices at a conceptual level.