Sanjay Kakar

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic and nonneoplastic diseases of the liver, biliary tree, pancreas, and gallbladder, it incorporates the most recent clinical, pathologic, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Hepatobiliary and Pancreas is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Presents clear delineations in challenging diagnoses for both nonneoplastic and neoplastic settings, illustrates novel tumor variants, uses updated terminology and society guidelines, and summarizes the role of molecular findings for diagnosis Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls Details the increasing use of molecular methods to diagnose cholestatic biliary liver conditions and other liver diseases of unknown etiology Notes critical recent terminology changes, such as the switch from non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated steatotic liver disease (MASLD) Elucidates novel variants of hepatocellular tumors and cholangiocarcinoma, and illustrates the integration of genomic findings in establishing the diagnosis and subclassification of tumors Features 1,600+ high-quality print images (with an additional 250+ images in the complimentary eBook), including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images Reflects the most recent information from the 6th edition WHO Classification of Tumours, Digestive System Tumours, the American Association for the Study of Liver Disease (AASLD), and the European Association for the Study of the Liver (EASL), including new AASLD guidelines for hepatocellular carcinoma (HCC) and EASL guidelines for cholangiocarcinoma Features a templated, highly formatted design; concise, bulleted text; key facts in each chapter; and an extensive index for easy reference Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud; additional digital ancillary content may publish up to 6 weeks following the publication date

The first title in the new Case-Based Approach to Diagnosis series, Gastrointestinal Pathology and Liver Metastasis offers a practical, real-world approach to this complex area of surgical pathology. Actual cases, highlighted by hundreds of high-quality clinical and histologic photographs, help you learn and retain key information, including which pathologic findings are clinically significant and which are not. Useful as both an everyday bench-side reference and as an authoritative review for certification and recertification exams, this new volume uses diagnostically relevant cases to teach how to evaluate and interpret even the most challenging lesions. Discusses advances in molecular diagnostic testing, its capabilities and its limitations, including targeted and personalized medicine Incorporates the latest TNM staging and WHO classification systems, as well as new diagnostic biomarkers and their utility in differential diagnosis, newly described variants, and new histologic entities Contains more than 700 high-quality, full color illustrations-a complete visual guide to each tumor or tumor-like lesion that assists in the recognition and diagnosis of any tissue sample under the microscope Presents extensively detailed information throughout, with descriptions of macroscopic features, microscopic findings, and cytopathology Incorporates relevant data from ancillary techniques such as immunohistochemistry, cytogenetics, and molecular genetics, providing you with all of the necessary tools required to master the latest breakthroughs in diagnostic technology An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

Free digital access available with every print purchase. See inside the book for more details. The primary goal of this fascicle is to be a practical reference for pathologists who review liver biopsies, a most challenging area of diagnostic surgical pathology. It is focused on diagnostic histopathology, discussing and lavishly illustrating disease patterns with an emphasis on differential diagnosis. The key aspects of clinical features, laboratory findings, and pathophysiology are woven into this book. The application and interpretation of special stains and immunohistochemistry are integrated into discussions of each disease pattern.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of neoplastic and nonneoplastic diseases of the digestive tract and accessory organs such as the pancreas and liver, it incorporates the most recent clinical, pathological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Hepatobiliary and Pancreas is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource. Analyzes hundreds of diagnoses, each of which include critical diagnostic information such as definitions, epidemiology, clinical presentation, macro- and microscopic features, differential diagnoses, and pathologic interpretation pearls. Features thorough updates throughout, including novel immunohistochemical markers and other ancillary techniques (such as BAP1, INSM1, Rb, albumin in situ hybridization) that play an increasingly critical role in improving diagnoses Addresses recent advances in molecular pathology-new diagnostic, immunohistochemical, molecular, and genetic techniques used for diagnosis, as well as new details about the genesis and activity of tumors in the liver, pancreas, and biliary systems Includes details from the 2019 WHO Classification of Tumors of the Digestive System regarding important changes to diagnostic techniques, identification of new variants of cancers, and immunohistochemical markers and ancillary techniques that improve diagnosis and treatment options Reflects recent WHO updates and updates from the AJCC's 8th Edition Cancer Staging Manual such as new terminology, new grading of neuroendocrine tumors and neuroendocrine carcinomas, and characteristic molecular alterations in hepatocellular adenoma, cholangiocarcinoma, and other tumors Uses a templated page layout, bulleted text, and a generous number of high-quality images to help practicing and in-training pathologists reach a confident diagnosis Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

The latest edition of Diagnostic Pathology: Hepatobiliary and Pancreatic has been completely updated, boasting new text, images, and terminology to keep you current with the latest knowledge in the field. Designed for both practicing pathologists and pathologists in training, it boasts a concise, organized format and numerous high-quality images to help you quickly address everyday challenges. New classification/terminology for biliary and pancreatic noninvasive intraductal tubular and papillary lesions Updates of variants, immunohistochemical diagnoses, diagnostic criteria, and novel molecular aspects for hepatocellular carcinoma Updates of molecular and immunohistochemical classification of multiple entities, including hepatic adenomas New grading scheme/terminology for pancreatic neuroendocrine tumors Immunohistochemical diagnosis of focal nodular hyperplasia Templated page layout, bulleted text, and a generous number of high-quality images for point-of-care clinical reference Expert Consult eBook version included, which allows you to search all of the text, figures, and references from the book on a variety of devices

For the surgical pathologist, this coverage of Liver Pathology presents practical information with ample discussion of differential diagnosis and use of special studies, where relevant, to engage pathologists in what you can do daily in practice. Topics include: Steatohepatitis: Histopathologic diagnosis; Regression and subclassification of cirrhosis; Autoimmune hepatitis and overlap syndrome; Liver transplant pathology: challenging diagnostic situations; Hepatocellular adenoma; Immunohistochemistry for the diagnosis of hepatocellular carcinoma; Histologic subtypes of hepatocellular carcinoma: diagnostics and clinical significance; Pediatric cholestatic disorders. Sanjay Kakar and Dhanpat Jain bring their expertise in liver pathology and lead a group of authors whose focus is on liver and GI pathology. The surgical pathologist has at hand in this issue the essential and most current aspects of liver pathology required for daily practice.