Sean B. Carroll

One of today's most accomplished biologists and gifted storytellers reveals the rules that regulate all lifeHow does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon. One of the most important revelations about the natural world is that everything is regulated—there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar—there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti Rules to heal our ailing planet. Bold and inspiring, The Serengeti Rules illuminates how life works at vastly different scales. Read it and you will never look at the world the same way again.

"Fascinating and exhilarating—Sean B. Carroll at his very best."—Bill Bryson, author of The Body: A Guide for OccupantsFrom acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the worldWhy is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world. Like every other species, we humans are here by accident. But it is shocking just how many things—any of which might never have occurred—had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death. This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

"Fascinating and exhilarating—Sean B. Carroll at his very best."—Bill Bryson, author of The Body: A Guide for OccupantsFrom acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the worldWhy is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world. Like every other species, we humans are here by accident. But it is shocking just how many things—any of which might never have occurred—had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death. This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

A unique opportunity for students to learn biology through stories told by one of the great science storytellers of our time: Sean B. Carroll. This enriching text follows the structure of an introductory biology course, with brief chapters that span the breadth of the life sciences. This gives maximum flexibility to assign a few stories, or all of them.

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions, and shows how their discoveries matter for our health and the health of the planet we depend upon. One of the most important revelations about the natural world is that everything is regulated--there are rules that regulate the amount of every molecule in our bodies and rules that govern the numbers of every animal and plant in the wild. And the most surprising revelation about the rules that regulate life at such different scales is that they are remarkably similar--there is a common underlying logic of life. Carroll recounts how our deep knowledge of the rules and logic of the human body has spurred the advent of revolutionary life-saving medicines, and makes the compelling case that it is now time to use the Serengeti Rules to heal our ailing planet. A bold and inspiring synthesis by one of our most accomplished biologists and gifted storytellers, The Serengeti Rules is the first book to illuminate how life works at vastly different scales. Read it and you will never look at the world the same way again.

The never-before-told account of the intersection of some of the most insightful minds of the 20th century, and a fascinating look at how war, resistance, and friendship can catalyze genius. In the spring of 1940, the aspiring but unknown writer Albert Camus and budding scientist Jacques Monod were quietly pursuing ordinary, separate lives in Paris. After the German invasion and occupation of France, each joined the Resistance to help liberate the country from the Nazis and ascended to prominent, dangerous roles. After the war and through twists of circumstance, they became friends, and through their passionate determination and rare talent they emerged as leading voices of modern literature and biology, each receiving the Nobel Prize in their respective fields. Drawing upon a wealth of previously unpublished and unknown material gathered over several years of research, Brave Genius tells the story of how each man endured the most terrible episode of the twentieth century and then blossomed into extraordinarily creative and engaged individuals. It is a story of the transformation of ordinary lives into exceptional lives by extraordinary events--of courage in the face of overwhelming adversity, the flowering of creative genius, deep friendship, and of profound concern for and insight into the human condition.

Sean Carroll explores how evolution has shaped nature's wondrous complexity and diversity, from insects to octopuses, from mice to men. We not only share nearly 99% of our genes with chimps, we also have some 35% in common with daffodils. Throughout much of the animal and even plant kingdoms, almost the same ancient genes code for almost the same proteins. And further, to everyone's astonishment, the genes involved in making the complex eyes of fruitflies are close matches to those involved in making the very different eyes of octopuses and people. So what leads to the nature's 'endless forms most beautiful'? The key to this mystery is being unravelled by 'Evo Devo' or the new science of evolutionary development biology. By looking at how a single-celled egg gives rise to a complex, multi-billion celled animal, Evo Devo is illuminating exactly how new species - butterflies and zebras, trilobites and dinosaurs, apes and humans - are made and evolved. The key, it turns out, is all about location and timing... For anyone who has ever pondered 'where did I come from', Endless Forms Most Beautiful explores our history, both the journey we have all made from egg to adult, and the long trek from the origin of life to the very recent origin of our species.

An award-winning biologist takes us on the dramatic expeditions that unearthed the history of life on our planet. Just 150 years ago, most of our world was an unexplored wilderness. Our sense of its age was vague and vastly off the mark, and much of the knowledge of our own species' history was a set of fantastic myths and fairy tales. In the tradition of The Microbe Hunters and Gods, Graves, and Scholars, Sean Carroll leads a rousing voyage that recounts the most important discoveries in two centuries of natural history: from Darwin's trip around the world to Charles Walcott's discovery of pre-Cambrian life in the Grand Canyon; from Louis and Mary Leakey's investigation of our deepest past in East Africa to the trailblazers in modern laboratories who have located a time clock in our DNA.

In 1809, when Darwin was born, much of the world was an unexplored wilderness. Our knowledge of the past was nonexistent, and our picture of our species' history little more than a set of fantastic myths and fairytales. But a new era was dawning. Five decades later, On the Origin of the Species was able to draw on the pioneering work of explorers and naturalists to produce a theory that revolutionized our conception of our world. And the revolution didn't stop with the publication of Darwin's masterwork. 150 years later, his 'dangerous idea' is still headline news, denied by many, capable of enraging and dividing, even as biologists decipher the 3-billion-year history of life as written in our very DNA. This book tells the stories of the most dramatic adventures and important discoveries in two centuries of natural history - from Alexander von Humboldt's epic journeys in South America to the hi-tech genome-reading projects making headlines today - and how they gave birth to and have nourished the evolution revolution.

For over a century, opening the black box of embryonic development was the holy grail of biology. Evo Devo -- Evolutionary Developmental Biology -- is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected. Perhaps the most surprising finding of Evo Devo is the discovery that a small number of primitive genes led to the formation of fundamental organs and appendages "in all animal forms." The gene that causes humans to form arms and legs is the same gene that causes birds and insects to form wings, and fish to form fins; similarly, one ancient gene has led to the creation of eyes across the animal kingdom. Changes in the way this ancient tool kit of genes is used have created all the diversity that surrounds us. Sean Carroll is the ideal author to lead the curious on this intellectual adventure -- he is the acknowledged leader of the field, and his seminal discoveries have been featured in Time and The New York Times.

Captivating and lucid, The Making of the Fittest delves deep into the DNA record to reveal not just how the fittest survive but also how they are made.

DNA on kaikkien olentojen rakennesuunnitelma - se sisältää arkielämän toimintaohjeet ja seuraavan sukupolven rakenteen. Kelpoisimman valmistus kertoo, miten uudet tulokset kiistatta osoittavat, että evoluutio on todellista, ja miten evoluutio toimii lajien, yksilöiden ja geenien tasolla.

DNA, the genetic blueprint of all creatures, is a stunningly rich and detailed record of evolution. Every change or new trait, from the gaudy colors of tropical birds to our color vision with which we admire them, is due to changes in DNA that leave a record and can be traced. Just as importantly, the DNA evidence has revealed several profound surprises about how evolution actually works.

An introduction to evolutionary developmental biology demonstrates how the many forms of animals evolved and came into being, documenting how the Evo Devo branch of science proved that all animal organs and appendages, from arms and legs to wings and fins, were created from a small number of primitive genes. Reprint.

In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.