Shirish Sangle

Sjögren’s syndrome is now considered pivotal in the spectrum of auto-immune disorders. It presents in a variety of guises, including fatigue, aches and pains, food and other allergies and not surprisingly is frequently misdiagnosed as, for example, ‘fibromyalgia, ‘M. E.’, glandular fever etc. It also frequently overlaps with other auto-immune conditions such as hypothyroidism (Hashimotos), Hughes Syndrome and coeliac disease. Diagnosis is especially important as it usually responds to treatment, notably with quinine derivatives (Plaquenil).

Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable. Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training.