Vartika Verma

Periodontal diseases are inflammatory diseases in which microbial etiologic factors induce a series of host responses that mediate inflammatory events. In susceptible individuals, dysregulation of inflammatory and immune pathways leads to chronic inflammation, tissue destruction and disease. Physiologic inflammation is a well-orchestrated network of cells, mediators and tissues. It is very important to consider the inflammatory / immune response as a whole, rather than many different modules working separately. As disease appears to be the result of loss of regulation and a failure to return to homeostasis, it is important to achieve a more complete understanding of the molecular and cellular events in this complex system.

In pathology, wound healing refers to healing of injured tissue by living tissue. A deep perception of clinical and biological variables affects the periodontal regeneration and allows the dental practitioner to redirect clinical and biological factors effectively to enhance clinical result and increase periodontal regeneration. Healing is ideal when there is acceptable aesthetics and appropriate function. Therefore, a meticulous knowledge regarding the relationship and nature of various periodontal tissues is needed to attain satisfactory healing which result in the development of new periodontal ligament, alveolar bone and cementum, and properly secured by gingival tissue.