Paul Agutter

A unique biographical review of the global contributors to field of anatomy Knowledge of human anatomy has not always been an essential component of medical education and practice. Most European medical schools did not emphasize anatomy in their curricula until the post-Renaissance era; current knowledge was largely produced between the 16th and 20th centuries. Although not all cultures throughout history have viewed anatomy as fundamental to medicine, most have formed ideas about the internal and external mechanisms of the body?influences on the field of anatomy that are often overlooked by scholars and practitioners of Western medicine. History of Anatomy: An International Perspective explores the global and ancient origins of our modern-day understanding of anatomy, presenting detailed biographies of anatomists from varied cultural and historical settings. Chapters organized by geographic region, including Africa, the Middle East, and Europe, review the lives of those that helped shape our current understanding of the human form. Examining both celebrated and lesser-known figures, this comprehensive work examines their contributions to the discipline and helps readers develop a global perspective on a cornerstone of modern medicine and surgery. Offers a comprehensive and multidisciplinary examination of the history of anatomyTraces the emergence of modern knowledge of anatomy from ancient roots to the modern eraFills a gap in current literature on global perspectives on the history of anatomyWritten by an internationally recognized team of practicing physicians and scholars History of Anatomy: An International Perspective is an engaging and insightful historical review written for anatomists, anthropologists, physicians, surgeons, medical personnel, medical students, health related professionals, historians, and anyone interested in the history of anatomy, surgery, and medicine.

In the last decade nucleo-cytoplasmic transport has developed into one of the most active areas of research in cell biology and its significance for cell biology as a whole has been recognized. It has led to elucidation of the mechanisms of major cellular functions such as protein synthesis and cellular differentiation. It is also helping to bring about a synthesis of ultrastructural, biochemical, molecular biological and biophysical approaches to the study of cellular organization and function. These theoretical advances have been made possible chiefly by advances in technology - improved methods of gene manipulation and sequencing, of monoclonal antibody production and the use of protein chemistry, of microscopy and of cell manipulation, including microinjection methods. Developments in molecular biology, such as the search for sequence - specific DNA binding proteins and the identification of their binding domains, have also furthered advances in cell biology and these areas have become increasingly integrated with some well-established areas of biochemistry. This book aims to be an introduction, for senior undergraduates and postgraduate biologists, to the field of nucleo-cytoplasmic transport and its relevance to cell biology and seeks to use recent advances in the field to illustrate the process by which modern scientific progress occurs - the importance of developing techniques for formulating problems as well as answering them and the integration of different approaches leading to the evolution of novel concepts. The author assumes a basic general knowledge of molecular and cell biology and of biochemistry, but provides all the necessary background for discussion of recent advances and in the final chapters discusses the actual and potential contributions of the field of nucleo-cytoplasmic transport to cell biology.

In the last decade nucleo-cytoplasmic transport has developed into one of the most active areas of research in cell biology and its significance for cell biology as a whole has been recognised. It has led to elucidation of the mechanisms of major cellular functions such as protein synthesis and cellular differentiation. It is also helping to bring about a synthesis of ultrastructural, biochemical, molecular biological and biophysical approaches to the study of cellular organisaton and function. These theoretical advances have been made possible chiefly by advances in technology - improved methods of gene manipulation and sequencing, of monoclonal antibody production and the use of protein chemistry, of microscopy and of cell manipulation including micro-injection methods. Developments in molecular biology, such as the search for sequence - specific DNA binding proteins and the identification of their binding domains, have also furthered advances in cell biology and these areas have become increasingly integrated with some well-established areas of biochemistry. This book aims to be an introduction, for senior undergraduates and postgraduate biologists, to the field of nucleo-cytoplasmic transport and its relevance to cell biology and seeks to use recent advances in the field to illustrate the process by which modern scientific progress occurs - the importance of developing techniques for formulating problems as well as answering them and the integration of different approaches leading to the evolution of novel concepts. The author assumes a basic general knowledge of molecular and cell biology and of biochemistry, but provides all the necessary background for discussion of recent advances and in the final chapters discusses the actual and potential contributions of the field of nucleo-cytoplasmic transport to cell biology.