Timothy D.W. Claridge

A Practical Guide to Structure Determination in Organic Chemistry offers a highly accessible and hands-on introduction to identifying the molecular structure of organic compounds from spectroscopic data. It sets out a systematic approach to using and integrating spectroscopic data in a way that helps the reader to develop their skills in interpreting MS, NMR, and IR spectra in order to solve structure determination problems. In-depth discussions of worked examples show how to effectively gather and evaluate clues from different types of spectra, and a set of practice problems allows students to apply these principles themselves to deepen their understanding. The book also offers insights into how more advanced NMR and MS techniques, including two-dimensional NMR and tandem mass spectral methods, are used and can provide clues for finalizing the assignment of molecular structure in challenging cases. Key features - Introduces a systematic approach for determining the molecular structure of organic compounds by drawing on data from different spectroscopic techniques - Exemplifies strategies for determining structures by working through detailed worked examples step-by-step - Provides more than 15 practice problems that increase in difficulty and allow the reader to build their skills in structural analysis - Includes a handy checklist of information that can be derived from different types of spectra and practical tips for interpreting real-world samples Digital formats and resources A Practical Guide to Structure Determination in Organic Chemistry is available for students and institutions to purchase in a variety of formats. The e-book and Science Trove offer a mobile experience and convenient access, along with functionality tools and navigation features: www.oxfordtextbooks.co.uk/ebooks

High-Resolution NMR Techniques in Organic Chemistry, Third Edition describes the most important NMR spectroscopy techniques for the structure elucidation of organic molecules and the investigation of their behaviour in solution. Appropriate for advanced undergraduate and graduate students, research chemists and NMR facility managers, this thorough revision covers practical aspects of NMR techniques and instrumentation, data collection, and spectrum interpretation. It describes all major classes of one- and two-dimensional NMR experiments including homonuclear and heteronuclear correlations, the nuclear Overhauser effect, diffusion measurements, and techniques for studying protein–ligand interactions. A trusted authority on this critical expertise, High-Resolution NMR Techniques in Organic Chemistry, Third Edition is an essential resource for every chemist and NMR spectroscopist.

High-Resolution NMR Techniques in Organic Chemistry describes the most important high-resolution NMR techniques that find use in the structure elucidation of organic molecules and the investigation of their behavior in solution. The techniques are presented and explained using pictorial formats wherever possible, limiting the number of mathematical descriptions. The emphasis is on the more recently developed methods of solution-state NMR spectroscopy with a considerable amount of information on implementation and on the setting of critical parameters for anyone wishing to exploit these methods.

An understanding of spectroscopic techniques in the analysis of chemical structures is essential to all chemistry degree courses. This new addition to the Oxford Chemistry Primers series provides the essential material needed by undergraduates, in a compact form. It will be beneficial to postgraduates in organic chemistry as reference material in their daily research.